BIO 581/581L - Transport Across Cell Membranes (3/2)

Practical and theoretical considerations of water and solute transport across cell membranes. Thorough discussion of the structure and function of major transport proteins including pumps, ion-coupled co-transporters and exchangers, voltage- and ligand-gated ion channels, water channels, and facilitative transporters. Examination of the role of transport proteins as they relate to physiological phenomena such as membrane excitability, vesicle fusion, nutrient absorption, and water homeostasis. Laboratory reinforces the principles and provides exposure to microinjection, ion-selective electrodes, electrophysiological methods (patch clamp and two-electrode voltage clamp), data acquisition, and data analysis.

Prerequisite(s): BIO 428/428L or ZOO 428/428L, CHM 329/CHM 329L, PHY 123/PHY 123L or PHY 133/PHY 133L.
Component(s): 3 lecture discussions. 2 three-hour laboratories.
Faculty: Eskandari.